New York Giants running back Ahmad Bradshaw will miss his second straight game Sunday at San Francisco due to a fractured bone in his right foot. Wide receiver Jerrel Jernigan will also miss the game with a hip injury.
As for the good news, defensive end Osi Umenyiora (knee) made full participation in practice after being limited earlier in the week and is listed as probably for Sunday, along with fullback Henry Hynoski (neck).
Wide receiver Hakeem Nicks, who missed last week's game with a strained hamstring, had his second straight day of limited participation and is listed as questionable along with rookie cornerback Prince Amukamara (foot), who will look to make his NFL debut against the 49ers. Center David Baas (knee) and offensive tackle Stacy Andrews (back) are also listed as questionable.